Area Elective - Chemical and Biological Engineering

Area Elective

Area Elective Courses

CHBI 310 – BIOCHEMISTRY II
Credits: 3
Prerequisites: CHBI 300

Biochemistry of signal transduction, glycolysis and gluconeogenesis, Krebs cycle, biochemistry of photosynthesis; metabolism of glycogen, fatty acids, nucleic acids, amino acids; DNA replication and repair; drug development

CHBI 332 – OPTIM CHEM & BIOL PROCESS
Credits: 3
Prerequisites:

Unconstrained and constrained optimization formulations: objective functions, models and constraints, search methods, applications to chemical and biological processes. Topics include model building, optimum equipment and plant design, optimizing process operations, and scheduling.

CHBI 350 – ST CHBI
Credits: 3
Prerequisites:

Selected Topic in Chemical and Biological Engineering.

CHBI 351 – ST CHBI
Credits: 3
Prerequisites:

Selected Topic in Chemical and Biological Engineering.

CHBI 390 – INDEPENDENT STUDY
Credits: 3
Prerequisites:

CHBI 395 – INDEPENDENT STUDY
Credits: 3
Prerequisites:

CHBI 405 – POLYMER ENGINEERING
Credits: 3
Prerequisites: CHEM 102 or consent of the instructor

Polymers, their synthesis and properties. Relationshios between molecular structure and properties. Rheology in polymer processing. Fabrication methods and applications.

CHBI 406 – BIOINFORMATICS
Credits: 3
Prerequisites: MATH 107 or consent of the instructor

The principles and computational methods to study the biological data generated by genome sequencing, gene expressions, protein profiles, and metabolic fluxes. Application of arithmetic, algebraic, graph, pattern matching, sorting and searching algorithms and statictical tools to genome analysis. Applications of Bioinformatics to metabolic engineering, drug design, and biotechnology.

CHBI 409 – BIOMATERIALS
Credits: 3
Prerequisites: (MBGE. 200 and (CHEM. 102 or CHEM. 103)) or consent of the instructor

Synthesis, characterization and functional properties of organic and inorganic biomaterials (polymers, metals/alloys, ceramics). Molecular and cellular interactions with biomaterials. Their biocompatibility, and stability in the body. Biological response to artificial implants. Drug-delivery systems and engineered tissues.

CHBI 411 – SUSTAINABLE ENERGY
Credits: 3
Prerequisites: CHBI 204 or consent of the instructor

Examine the technologies, environmental impacts and economics of main energy sources of today and tomorrow including fossil fuels, nuclear power, biomass, geothermal energy, hydropower, wind energy, and solar energy. Comparison of different energy systems within the context of sustainability. Hydrogen economy and fuel cells.

CHBI 412 – CATALYSIS AT SURFACES
Credits: 3
Prerequisites:

Adsorption on surfaces, structural and dynamic considerations in adsorption, thermodynamics of adsorption, methods for catalyst characterization, pore structure and surface area, surface chemistry of catalysis, metals, highly dispersed catalysts, industrial examples with emphasis on energy production

CHBI 415 –REFINING TECHNOLOGIES
Credits: 3
Prerequisites:

Crude oil and biomass refining technologies. Fractionation, catalytic- and thermo- cracking, gasoline and diesel upgrading and other side processes in crude oil refining; gasification, pyrolysis, transesterification and condensation processes in biomass refining; economical and environmental factors in refining.

CHBI 416 –BIOTECHNOLOGY
Credits: 3
Prerequisites: MBGE 200 or consent of the instructor

Recombinant DNA, enzymes and other biomolecules. Molecular genetics. Commercial use of microorganisms. Cellular reactors; bioseparation techniques. Transgenic systems. Gene therapy. Biotechnology applications in environmental, agricultural and pharmaceutical problems.

CHBI 417 –DRUG DESIGN
Credits: 3
Prerequisites:

Drug design consists of identifying a target (DNA, RNA, proteins) that is known to cause a certain disease and selectively inhibiting or modifying its activity by binding a drug molecule to a specified location on that target. In this course, computational techniques for designing such a drug molecule will be taught. The topics to be covered are: Identification of the active part. Forces involved in drug-receptor interactions. Screening of drug libraries. Use of different software to determine binding energies. Identifying a lead molecule. Methods of refining a lead molecule for better suitability. Case studies: A survey of known drugs, success and failure stories.

CHBI 420 –BIOMOLEC STRUC, FUNC&DYN.
Credits: 3
Prerequisites: Instructor Consent Required

Relationship between structure, function and dynamics in biomolecules. Overview of the biomolecular databases and application of computational methods to understand molecular details, interactions; networks. Principles of computational modeling and molecular dynamics of biological systems.

CHBI 422 –COMPUTATIONAL STRUCTURAL BIO
Credits: 3
Prerequisites: ENGR 201 and CHBI 300

Introduction to the principles of structural biology, and computational techniques used to investigate the structure, dynamics and function of biological systems. Description of theoretical and computational tools to investigate relevant problems in the domain of biophysics and biochemistry. The fundamentals structure determination techniques, energy functions, molecular dynamics simulations, molecular docking and techniques to predict the protein structure and protein-protein interactions.

CHBI 424 –MOLECULAR CHRONOBIOLOGY
Credits: 3
Prerequisites: CHBI 300 or MBGE 300

Basic principles of chronobiology, clock genes, the suprachiasmatic nucleus, peripheral clocks, circadian photoreception, clock transcription factors and redundancy, circannual rhythms and photoperiodism, chronopharmacology, clocks, microbes and immunity human circadian rhythms.

CHBI 427 –ROCKET PROPULSION
Credits: 3
Prerequisites: MECH 302 or CHBI 302 or consent of the instructor

The principles of rocket propulsion system design and analysis. The fundamental aspects of physics and chemistry of rocket propulsion will be discussed. The concentration will be on the design and analysis of chemical propulsion systems including liquids, solids and hybrids. Non-chemical propulsion concepts such as electric and nuclear rockets will also be covered. Finally launch vehicle design and optimization issues including trajectory calculations will be discussed.

CHBI 430 –SYSTEM BIOLOGY
Credits: 3
Prerequisites:-

Reconstruction of metabolic network from genome information and its structural and functional analysis, computational models of biochemical reaction networks; system biology in drug discovery and proteomics, flux balance analysis; modeling of gene expression; system biology in artificial intelligence.

CHBI 431 –MODEL & SIML CHEM BIO PRO
Credits: 3
Prerequisites: Instructor Consent Required

Modeling concepts and tools for chemical and biological systems. Steady state and transient modeling and simulation. MATLAB based case studies. Selected topics from the curriculum such as reaction stoichiometry, kinetics modeling, reactors, equation of state, phase equilibria, staged operations, fluxes, diffusion and convection, parameter estimation.

CHBI 438 –INTERMOLEC&SURFACE FORCES
Credits: 3
Prerequisites: CHEM 302 or consent of the instructor

Intermolecular forces which govern self-organization of biological and synthetic nanostructures. Thermodynamic aspects of strong (covalent and coulomb interactions) and weak forces (dipolar, hydrogen bonding). Self-assembling systems: micelles, bilayers, and biological membranes. Computer simulations for ôhands-onö experience with nanostructures.

CHBI 440 –NANOSTRUCT MATER FOR ENERGY
Credits: 3
Prerequisites: CHEM 302 or CHBI 308 or consent of the instructor

Advanced nanostructured materials used in energy conversion and production, membrane electrode assemblies for fuel cells, photovoltaic devices, nanoporous materials for acoustic and thermal insulation, energy storage devices such as lithium ion batteries.

CHBI 441 – PROCESS SYSTEMS ENGINEERING
Credits: 3
Prerequisites: Instructor Consent Required

Concepts and fundamentals of optimization, numerical algorithms for (un-) constrained optimization, concepts of mathematical programming (LP,NLP,MINLP), examples of optimal chemical/biological process design, computer-aided simulations.

CHBI 450 – ST CHBI
Credits: 3
Prerequisites:

Selected Topic in Chemical and Biological Engineering.

CHBI 451 – ST CHBI
Credits: 3
Prerequisites:

Selected Topic in Chemical and Biological Engineering.

CHBI 484 – TISSUE ENGINEERING
Credits: 3
Prerequisites:

The fundamentals of tissue engineering at the molecular and cellular level; techniques in tissue engineering; problems and solution in tissue engineering; transplantation of tissues in biomedicine using sophisticated equipments and materials; investigation of methods for the preparation of component of cell, effect of growth factors on tissues.

CHBI 485 – MOL MODEL & SIMUL
Credits: 3
Prerequisites: CHBI 204 or consent of the instructor

Principles of molecular modeling in chemical engineering applications; fundamentals for molecular simulation of adsorption and diffusion processes in nanoporous materials; molecular dynamics methods for gas transport in nanopores; Monte Carlo methods for equilibrium based gas separations; molecular modeling of zeolites and metal organic frameworks for gas storage.

CHBI 506 – BIOINFORMATICS
Credits: 3
Prerequisites:

The principles and computational methods to study the biological data generated by genome sequencing, gene expressions, protein profiles, and metabolic fluxes. Application of arithmetic, algebraic, graph, pattern matching, sorting and searching algorithms and statistical tools to genome analysis. Applications of Bioinformatics to metabolic engineering, drug design, and biotechnology.

CHBI 510 –INDUSTRIAL MICROBIOLOGY
Credits: 3
Prerequisites:

Key aspects of microbial physiology; exploring the versatility of microorganisms and their diverse metabolic activities and products; industrial microorganisms and the technology required for large-scale cultivation.

CHBI 511 –SUSTAINABLE ENERGY
Credits: 3
Prerequisites:

CHBI 516 –BIOTECHNOLOGY
Credits: 3
Prerequisites:

CMSE 520 –BIOMOLEC STRUC, FUNC&DYN.
Credits: 3
Prerequisites: CMSE 501 or consent of the instructor

Relationship between structure, function and dynamics in biomolecules. Overview of the biomolecular databases and application of computational methods to understand molecular interactions; networks. Principles of computational modeling and molecular dynamics of biological systems.

CHEM 410 –POLYMERS
Credits: 3
Prerequisites: CHEM 102 or consent of the instructor

Physicochemical concepts of the formation and properties of macromolecules; polymerization reactions and techniques, molecular weight distributions, chemical and physical characterization of macromolecules; structure-morphology-property relationships in multiphase polymeric systems; processing techniques and applications of commercial thermoplastic and thermosetting polymers.

MBGE 210 –GENE STRUCTURE AND FUNCTIONS
Credits: 3
Prerequisites: MBGE 110 or CHBI 300

Methods in molecular biology and genetic engineering, chromosomes, extrachromosomal replicons, transposable elements and retroviruses, repair systems, somatic DNA recombination and hypermutation in the immune system, mRNA stability and localization, catalytic RNA and operons.